Friday, May 31, 2013

Can Humans Really Feel Hot and Cold?

If you compare the feeling of touching a piece of metal versus a piece of paper, the metal will always seem cooler, even if both objects are actually the same temperature. So what gives? It turns out that what we're really feeling as cold when we touch something is actually an object's increased ability to conduct thermal energy away from our skin.

Temperature is technically just a measurement of how much atoms and molecules in a given object are moving. The more movement, the hotter it feels. And since metal is a good conductor, it actually pulls thermal energy away from our skin when touched, causing our thermo-receptive nerves to interpret the loss of energy as the object being cold. So maybe meteorologists should start providing forecasts based on how quickly our bodies will gain and lose thermal energy throughout the day, instead of it being hot or cold. Or, maybe not.

Source: http://gizmodo.com/can-humans-really-feel-hot-and-cold-510473773

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Alterra captures the Capitol Square with more than coffee - Isthmus ...

When you order a coffee from the coffee bar portion of Alterra, where fresh cups are produced one at a time like all the cool coffeehouses do it now, you sort of hover near the bar and wait. When you order food and choose to sit at a table outside, your food is brought to you by table number. But when you do both? Well, you figure it out, because I had to ask. (There's no good way.)

The newest location for Milwaukee-based Alterra is on the Square in Tenney Plaza, and it wants to be your destination for almost everything downtown. Brewed coffee, coffee beans, Wi-Fi, smoothies, breakfast, lunch, dessert and even a beer after work ? yes, Alterra aims for all of these. But its success varies at achieving the diverse goals.

For a hot cup of coffee, the aforementioned coffee bar offers pour-overs of a small selection of beans and assures a fresh, rich cup every time ? even if you have to wait a little longer than for a standard brew. The dark, rich Maximilian roast is a personal favorite, but if you prefer a lighter roast, Del Sol is juicy and invigorating. Iced coffee, however, lacks the smooth, full body of the best cold-processed versions in town. (4 & 20, Madison Sourdough and Crema Cafe come to mind.)

Bakery is another strong suit, with house-made breads and pastries coming fresh from the Bayview location daily. A lemon-blueberry scone featured strong flavors of both, topped with crystals of sugar for a pleasant crunch. Closer to Cinco de Mayo, a cinnamon-guajillo chile brownie with a layer of dulce de leche was as sweet and decadent as you'd imagine, with the pepper bringing only the flirtation of heat.

Unfortunately, a slick-looking soft pretzel is inexcusably chewy, even after being warmed up, and bland besides. The chocolate croissant is equally featureless.

There ends the purview of the average coffee shop ? oh, but yes, the Wi-Fi is also good, if the number of laptops is any indication. The rest of the day's service is a mix of bonus points and overreach.

Bonus points: the biscuits. They're massive, they're good ? maybe a little dry ? and they serve as a fine vessel for breakfast sandwiches. Here's a puzzler, though: If the bacon biscuit is essentially the cheesy biscuit plus bacon, why do they cost the same? Either way, be careful; it comes out steaming hot. Take your time and figure out that bacon math.

Burritos are all over the menu at Alterra, and this is the disappointing overreach. Combinations like jerk chicken and potato, or eggs and sausage (they are specials, but tend to stick around for a while), sound great. But the latter was an indistinct agglomeration, and the former was too distinct by half, with the jerk chicken and potato split down the middle like boys and girls at a junior high dance.

Alterra's burritos are just not very good. Maybe a step above something fast-casual like Panera, with the character pressed and toasted right out of them.

A decent pesto mozzarella sandwich arrives with gooey, molten cheese in a bun the size and shape of a long john that envelops the fillings; call it a Haute Pocket. It's better by far than the tomato basil turkey sandwich, featuring both an odd (but flavorful) basil lemon cream cheese and melted provolone. This one is unpleasantly slippery, overloaded with moisture and goo.

All the unfulfilled promise of lunch is reversed with the smoothie, a vastly overexposed segment of the drink market that turns unexpectedly into something worth ordering in Alterra's hands. The mango peach ginger version tastes of all three, with recognizable yogurt notes underneath. I'd order one of these over most of Jamba Juice's menu.

And for something with a little more oomph, there's always the Cortado Imperial Coffee Stout, brewed with Alterra's beans by Madison's own One Barrel Brewing. It's a lovely beer, with no sharp edges and plenty of smooth coffee flavor. One barista told me she's actually seen someone order one at seven in the morning. There's also a pale ale that apparently sells almost as well, but I don't see how that's possible with something as charming as the Cortado on the menu.

As an all-occasion cafe, Alterra's successes can easily get lost in the hubbub. The best bites I took there were in its first few days, before I was officially reviewing it: a silky smoked salmon sandwich with capers and cream cheese, and a falafel burger with a thin raita-esque sauce. I'd say I liked Alterra before it was cool, but it's been a hotspot since the day it opened, and so popular you might not even notice its flaws.

Source: http://www.thedailypage.com/isthmus/article.php?article=40051

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GSK bets on chimp virus with $321 million vaccines buy

By Ben Hirschler

LONDON (Reuters) - GlaxoSmithKline is betting on a new vaccine technology based on chimpanzee viruses by acquiring Swiss-based Okairos for 250 million euros (321 million U.S. dollars) - the latest bolt-on biotech buy by a big drugmaker.

Britain's largest pharmaceuticals group said on Wednesday that the privately owned company's know-how was expected to play an important role in GSK's development of vaccines to both prevent and treat diseases.

Okairos was spun out from Merck & Co in 2007 and has laboratories in Rome and Naples, with headquarters in Basel.

It specializes in making vaccines that target the immune system's CD8 T-cells - an approach that could yield preventative vaccines against several intractable infectious diseases, including hepatitis C, and also help fight cancer.

It does this by delivering genetic material using deactivated chimpanzee-derived adenoviruses that produce a very strong response against target diseases.

Adenoviruses, which cause the common cold, have long been studied as a useful delivery vehicle for genetic material - but they are so common that many people already have antibodies against them.

Chimp viruses, which are not so easily detected by the body's immune system, have an advantage since they can operate for longer and therefore elicit a powerful T-cell response.

The Okairos technology has already been tested in clinical studies involving more than 700 subjects, including mid-stage Phase II programs in hepatitis C and malaria.

A hepatitis C shot could be particularly promising commercially, since there is currently no vaccine and treating the condition with drugs has become a multibillion-dollar business.

Okairos also has early stage products for diseases such as respiratory syncytial virus (RSV), tuberculosis, ebola and HIV.

NEW GENERATION OF VACCINES

The real attraction lies less in individual products than in the company's technology platform, which GSK hopes to exploit within its own vaccine development programs.

As such, the deal represents a long-term investment in a promising new scientific area, rather than one that will yield immediate financial rewards.

Christophe Weber, GSK's head of vaccines, said the acquisition of Okairos was "expected to contribute to the development efforts for an exciting new generation of vaccines".

GSK's Chief Executive Andrew Witty said earlier this year he had a "very low appetite" for acquisitions but, like many rivals in the industry, his company is constantly looking for bolt-on transactions to boost its pharmaceuticals, vaccines and consumer healthcare operations.

Last November, for example, GSK agreed to spend $1 billion to raise the stakes it holds in Indian and Nigerian consumer healthcare subsidiaries.

Smaller British rival AstraZeneca has a more urgent need for acquisitions, given its thin pipeline of new medicines to replace those losing patent protection. It agreed on Tuesday to pay up to $443 million for Omthera Pharmaceuticals, a U.S.-based specialist in fish oil-derived medicine.

Okairos's venture capital investors include BioMedInvest, the Boehringer Ingelheim Venture Fund, LSP, Novartis Venture Funds and Versant Ventures.

($1 = 0.7779 euros)

Source: http://news.yahoo.com/gsk-bets-chimp-virus-321-million-vaccines-buy-145459050.html

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Thursday, May 30, 2013

TechCrunch In The Balkans

tc balkansAre you in Bulgaria, Serbia, Croatia, or Slovenia? Have I got a treat for you. In an effort to spread the good word about TC in the rest of Europe, I will be rolling through Sofia, Belgrade, Zagreb, and Ljubljana at the beginning of July for a series of informal meet-ups. If you’re in those cities, I want you to attend! Assisting in the planning is Netokracija?/?Netocratic, the “TechCrunch of Southeast Europe.” They will provide us with locations and more specific timing but as it stands we expect to have some free beer, lots of sunshine, and a great chance to talk about your startup in an informal setting. We’ll also be scouting for Disrupt entrants for Disrupt Berlin in October. These will be informal meetups where I’ll talk a little bit about TechCrunch and getting the attention of media outside your own country and we can talk startups, entrepreneurship, and funding all night long. To RSVP for Sofia on July 1 click here.?Co-hosted by ?Netokracija / Netocratic & Eleven To RSVP for Belgrade on July 2 click here.?Hosted by?Netokracija?/?Netocratic. To RSVP for Zagreb on July 3 click here.?Hosted by?Netokracija?/?Netocratic. To RSVP for Ljubljana on July 5 click here.?Hosted by Netokracija / Netocratic. Interested in sponsoring the event? Please contact organizer Ivan Brezak Brkan, head of MemeMedia, directly. We’ll have much more information soon, but until then RSVP and get your product ready for our Southeast Euro Trip! Special thanks to our main sponsor, the .me domain.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Da3PK2iaYMk/

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development of new eCommerce Business | eCommerce ...

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As Internet Business Experts working in the?development of new eCommerce Business?for many years, ?Building own internet projects and eCommerce projects for large corporations.?Now we want partner with you and?fully develop your Internet Project to get the full potential of your online business.

To let us participate in your project we will cover all the cost of creation or edition and full development of the online business project

Also we will handle all processes on the Internet , while you handle your Company business,?And when the project start to?generate business?we will receive a percentage of sales?during agreed time to recover our investment?and of course also to earn money

To seal each alliance?we need a initial security payment?and also a minimum period of collaboration, thats all!

We will make your online business generate sales, and this will mean we make money.?working on a flexible and advantageous way?for the entrepreneurs

We know that our work system is not usual but really we seek that entrepreneurs feel that we are a partner, not a supplier?and so create a long-term relationship?and so fully develop each project ,

Really develop an online business is no question of a few weeks, we need several months to enable online sales and?once activated the online business sales,?we must continue to work to preserve and boost business because?Internet business is permanently in motion,

We want to go along with the?entrepreneurs in the full Online Business Development and apply our online business solutions over ecommerce companies to manage the entire internet business process and ensure maximum profitability?for entrepreneurs and for us too

Check now our eCommerce Consulting Program

Now if you fit with our work philosophy and want to Create, Expand or Boost your eCommerce business in partnership with us, let us know you want to collaborate.

Source: http://ecommerce-investments.com/development-ecommerce-business/?utm_source=rss&utm_medium=rss&utm_campaign=development-ecommerce-business

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Wednesday, May 29, 2013

News Corp unveils logo of impaired publishing unit

(AP) ? News Corp. on Tuesday unveiled a friendlier-looking logo for the publishing division as it prepares to split the struggling newspaper and book unit from its TV and movie business by the end of June.

The unveiling, at a one-day meeting with investors in New York, followed the company's recent disclosure to securities regulators that the publishing unit would book an impairment charge of up to $1.4 billion this quarter before being spun off as a separate, publicly traded company.

The logo, in cursive lettering, is based on the handwriting of founder Rupert Murdoch and his father. It replaces the striped globe of the current News Corp. brand.

Since the split was announced last June, News Corp.'s stock has climbed 65 percent, beating out peers like The Walt Disney Co. The Standard & Poor's 500 Index has risen 26 percent over the same period. Many investors believe the struggling newspaper company will no longer be a drag on growth of the entertainment businesses.

On Tuesday, the chief executive of the publishing group, which will continue to be called News Corp., touted the unit's future as a separate entity while acknowledging its difficulties as print advertising continues to decline across the industry.

"We're certainly not naive about the challenges facing some of our newspapers," said CEO Robert Thomson, former managing editor of The Wall Street Journal, which will be part of new News Corp. after the split. "We are in the midst of a transformation of those businesses. Costs are being confronted."

Murdoch said that part of the plan for the publishing side is to raise subscription prices to readers. He argued that The Wall Street Journal charges far less than The New York Times, for example. The Wall Street Journal also intends to expand its audience by publishing more foreign-language translated editions.

Murdoch did not hold out hope for an advertising turnaround for print newspapers, whose ad revenue has been siphoned off by Web-based companies like Google Inc. and Facebook Inc.

"We're being very realistic and not expecting any big expansion," he said. "There's no doubt the Internet has taken a lot of business."

The investor day was meant to reassure investors about the value of the new News Corp. It will contain the company's newspapers in the U.S., Britain and Australia; Dow Jones & Co., which owns The Wall Street Journal; its for-profit education business, Amplify; book publisher HarperCollins; and TV assets in Australia.

A separate company, to be called 21st Century Fox, will house its 20th Century Fox movie studio, TV channels such as Fox News and Fox Sports 1, and its investment in overseas TV providers like Sky Deutschland and Sky Italia. The entertainment company's logo, featuring Hollywood-style spotlights, was unveiled earlier this month.

The presentation followed a series of confidence-building announcements focused on the publishing spin-off.

News Corp. said in March the publishing unit would have $2.6 billion in cash and no debt, and on Friday it said the unit was authorized to buy back $500 million in shares, which is seen as buttressing its share price if there is a sell-off once existing shareholders are distributed new shares in the publishing company.

Analyst Todd Juenger of Bernstein Research said the stock market was putting little to no value on the publishing side in a research note Tuesday.

He valued 21st Century Fox at $34 per share? slightly higher than the $33.24 News Corp. shares closed at Tuesday ? and $6 per share for the publishing unit.

He suggested buying shares now to get publishing unit shares "for free," or waiting to "scoop up" publishing shares in case there is a sell-off on June 28, the date of the split. "If new News gets left for dead ... then scoop up new News at a bargain price," he recommended.

Dow Jones CEO Lex Fenwick also talked about new products that take aim at Bloomberg's financial data and news services in Tuesday's presentation. A product called DJX will include a wire service that gives institutional subscribers a 2-minute head start on news broken by The Wall Street Journal and Dow Jones reporters.

Fenwick said the new News Corp. has a "huge opportunity" if it can expand on its less than 1 percent market share of what he said was $40 billion in spending every year by financial institutions on such niche data and news platforms.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-05-28-New%20News%20Corp/id-8e700e7728a34eeaa7f2c01dbc7ba1b4

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EU countries now free to arm Syrian rebels (CNN)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/308798019?client_source=feed&format=rss

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Google's Rad Skee-Ball Game Turns Your Phone Into a Wii Remote

Google's Rad Skee-Ball Game Turns Your Phone Into a Wii Remote

God bless the whimsical programers over at Google who are forever finding fun ways for us to waste our days. Click this link to check out the Chrome team's latest experiment, which pairs your computer and your phone so that you can play an awesome game of Skee-Ball. It's called Roll It, and it's wonderful.

Read more...

    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/mXVFgnhZkHA/googles-rad-skee-ball-game-turns-your-phone-into-wii-r-510355552

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Engineering students use dance to solve problems

AAA??May. 29, 2013?7:27 AM ET
Engineering students use dance to solve problems
AP

In this April 29, 2013, photo, Billy Siegenfeld, Northwestern University Professor of Dance, center right, and dance instructor Jordan Kahl demonstrate swing dance steps for engineering students, in Evanston, Ill. The students are learning to swing dance in a for-credit class called Whole Body Thinking. They say the class is teaching them to think on their feet and work collaboratively with dance partners _ skills they say will help make them better engineers. (AP Photo/Teresa Crawford)

In this April 29, 2013, photo, Billy Siegenfeld, Northwestern University Professor of Dance, center right, and dance instructor Jordan Kahl demonstrate swing dance steps for engineering students, in Evanston, Ill. The students are learning to swing dance in a for-credit class called Whole Body Thinking. They say the class is teaching them to think on their feet and work collaboratively with dance partners _ skills they say will help make them better engineers. (AP Photo/Teresa Crawford)

In this April 29, 2013, photo, Andy Nwaelele, a biomedical engineering major, left, and dance partner Omowunmi Odutola practice wing dance steps during a Northwestern University class for engineering students called Whole Body Thinking in Evanston, Ill. The students say the class is teaching them to think on their feet and work collaboratively with dance partners _ skills they say will help make them better engineers. (AP Photo/Teresa Crawford)

In this April 29, 2013, photo, Jeremy Halpern, center, a civil engineering major, swing dances with Ali Lamens during a Northwestern University class called Whole Body Thinking, in Evanston, Ill. The students say the class is teaching them to think on their feet and work collaboratively with dance partners _ skills they say will help make them better engineers. (AP Photo/Teresa Crawford)

In this April 29, 2013 photo, Northwestern University engineering students Emil Klosowiak, left, and Ali Lamens swing dance during a for-credit class called Whole Body Thinking, at the McCormick School of Engineering in Evanston, Ill. The students say the class is teaching them to think on their feet and work collaboratively with dance partners _ skills they say will help make them better engineers. (AP Photo/Teresa Crawford)

(AP) ? Engineering students at Northwestern University are getting a leg up on the competition. They're learning to swing dance in a for-credit class called Whole Body Thinking.

Joe Holtgreive (HOHLT'-greev), an assistant dean at the McCormick School of Engineering, started the class to help future engineers break outside their comfort zone.

Holtgreive says the course, led by Northwestern University Professor of Dance Billy Siegenfeld (SEE'-gen-feld), is teaching students known for left-brain thinking to use more of the right side of their brains.

The students include biomedical, mechanical and chemical engineering majors who say they're learning more than dance. They say the class is teaching them to think on their feet and work collaboratively with dance partners ? skills they say will help make them better engineers.

See the video here: http://bit.ly/12O445R

Associated PressNews Topics: General news, Oddities, Math and science education, Amateur performance, Science, School curricula, Education, Social affairs, Hobbies, Recreation and leisure, Lifestyle

Source: http://hosted2.ap.org/APDEFAULT/aa9398e6757a46fa93ed5dea7bd3729e/Article_2013-05-29-Swing%20Dancing%20Engineers/id-ec75679c901947b8b2578a8549785fd6

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Tuesday, May 28, 2013

IRS Demanded Tea Party Explain Why They Didn?t Campaign For Democrat In New Mexico Governor Race?

Of course the IRS made no such demands from liberal groups.

(CNSNews.com) ? The Internal Revenue Service,?in a letter dated November 16, 2011, asked the Albuquerque Tea Party why it didn?t host a ?candidate rally? in 2010 for the lone Democratic gubernatorial candidate in New Mexico after it had hosted a ?question and answer forum? for the Republican candidates.

On the Democrat side, then-Lt. Gov. Diane Denish was running for New Mexico governor unopposed, but five Republicans were running in the primary for the opportunity to face Denish in November.

On page four of the IRS letter, question 8 asked the Albuquerque Tea Party:

?In describing your Event Rallies you stated that you hosted a question and answer forum with the GOP Primary Candidates for Governor of the state, and that not all GOP candidates attended. You stated that since there was only one candidate in the Democratic primary, there was no comparison to be made in the primary.?

In Question 8a of the letter, the IRS directed the Albuquerque group to ?Describe in detail the GOP Event Rally, including questions asked, and state the reasons you did not have a candidate rally for the lone Democratic candidate.?

Keep reading?

Source: http://weaselzippers.us/2013/05/28/irs-demanded-tea-party-explain-why-they-didnt-campaign-for-democrat-in-new-mexico-governor-race/

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Monday, May 27, 2013

I want to buy a house but need a private lender due to bankruptcy in ...

Sorry, Readability was unable to parse this page for content.

Source: http://www.zillow.com/advice-thread/I-want-to-buy-a-house-but-need-a-private-lender-due-to-bankruptcy-in-maryland/493990/

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John Tomic, Bernard Tomic's Father, Barred From Access To French Open

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: A general view over Philippe Chatrier court as Rafael Nadal of Spain serves in his Men's Singles match against Daniel Brands of Germany during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Matthew Stockman/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Spain's Rafael Nadal celebrates after winning the second set against Germany's Daniel Brands during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MIGUEL MEDINA (Photo credit should read MIGUEL MEDINA/AFP/Getty Images)

  • TENNIS-FRA-OPEN-WOMEN

    Denmark's Caroline Wozniacki hits a backhand shot to Britain's Laura Robson during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / PATRICK KOVARIK (Photo credit should read PATRICK KOVARIK/AFP/Getty Images)

  • TENNIS-FRA-OPEN-WOMEN

    Germany's Mona Barthel returns to Germany's Angelique Kerber during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MARTIN BUREAU (Photo credit should read MARTIN BUREAU/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    France's Gael Monfils stretches for a shot against Czech Republic's Tomas Berdych during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / THOMAS COEX (Photo credit should read THOMAS COEX/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Czech Republic's Tomas Berdych hits a forehand shot to France's Gael Monfils during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / THOMAS COEX (Photo credit should read THOMAS COEX/AFP/Getty Images)

  • TENNIS-FRA-OPEN-WOMEN

    Germany's Mona Barthel returns to Germany's Angelique Kerber during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MARTIN BUREAU (Photo credit should read MARTIN BUREAU/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Czech Republic's Tomas Berdych serves to France's Gael Monfils during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / THOMAS COEX (Photo credit should read THOMAS COEX/AFP/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Rafael Nadal of Spain holds his head during his Men's Singles match against Daniel Brands of Germany during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Getty Images/Getty Images)

  • TENNIS-FRA-OPEN-WOMEN

    Germany's Angelique Kerber returns to Germany's Mona Barthel during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MARTIN BUREAU (Photo credit should read MARTIN BUREAU/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Germany's Daniel Brands to Spain's Rafael Nadal during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MIGUEL MEDINA (Photo credit should read MIGUEL MEDINA/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Spain's Rafael Nadal reacts after a point against Germany's Daniel Brands during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / THOMAS COEX (Photo credit should read THOMAS COEX/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    The feet of Spain's Rafael Nadal hits a return to Germany's Daniel Brands during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MIGUEL MEDINA (Photo credit should read MIGUEL MEDINA/AFP/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Jo-Wilfried Tsonga of France serves in his Men's Singles match against Aljaz Bedene of Slovenia during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Julian Finney/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Spain's Rafael Nadal returns to Germany's Daniel Brands during their French Tennis Open first round match against to at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MIGUEL MEDINA (Photo credit should read MIGUEL MEDINA/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Spain's Rafael Nadal is given a towel after a point against Germany's Daniel Brands during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / THOMAS COEX (Photo credit should read THOMAS COEX/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Spain's Rafael Nadal hits a backhand shot to Germany's Daniel Brands during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / THOMAS COEX (Photo credit should read THOMAS COEX/AFP/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Daniel Brands of Germany plays a forehand in his Men's Singles match against Rafael Nadal of Spain during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Getty Images/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Sergiy Stakhovsky of Ukraine serves in his Men's Singles match against Richard Gasquet of France during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Julian Finney/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Rafael Nadal of Spain celebrates match point in his Men's Singles match against Daniel Brands of Germany during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Getty Images/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    France's Richard Gasquet (R) shakes hand with Ukraine's Sergiy Stakhovsky after their French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / PATRICK KOVARIK (Photo credit should read PATRICK KOVARIK/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Finland's Jarkko Nieminen returns to France's Paul-Henri Mathieu during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MARTIN BUREAU (Photo credit should read MARTIN BUREAU/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    France's Gael Monfils returns to Czech Republic's Tomas Berdych during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MIGUEL MEDINA (Photo credit should read MIGUEL MEDINA/AFP/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Bojana Jovanovski of Serbia plays a backhandduring her Women's Singles match against Barbora Zahlavova Strycova of Czech Republic during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Matthew Stockman/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Robin Haase of Netherlands in action during his Men's Singles match against Kenny De Schepper of France during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Julian Finney/Getty Images)

  • TENNIS-FRA-OPEN-WOMEN

    Russia's Ekaterina Makarova hits a forehand shot to Russia's Svetlana Kuznetsova during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / KENZO TRIBOUILLARD (Photo credit should read KENZO TRIBOUILLARD/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    France's Gael Monfils dives in a try to return to Czech Republic's Tomas Berdych during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / THOMAS COEX (Photo credit should read THOMAS COEX/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Ukraine's Sergiy Stakhovsky hits a backhand shot to France's Richard Gasquet during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / PATRICK KOVARIK (Photo credit should read PATRICK KOVARIK/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    France's Richard Gasquet hits a backhand shot to Ukraine's Sergiy Stakhovsky during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / PATRICK KOVARIK (Photo credit should read PATRICK KOVARIK/AFP/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Philipp Petzschner of Germany rests during his Men's Singles match against Marin Cilic of Croatia during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Matthew Stockman/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    France's Richard Gasquet serves to Ukraine's Sergiy Stakhovsky during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / PATRICK KOVARIK (Photo credit should read PATRICK KOVARIK/AFP/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Laura Robson of Great Britain plays a forehand in her Women's Singles match against Caroline Wozniacki of Denmark during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Julian Finney/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Laura Robson of Great Britain plays a backhand in her Women's Singles match against Caroline Wozniacki of Denmark during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Julian Finney/Getty Images)

  • TENNIS-FRA-OPEN-WOMEN

    Denmark's Caroline Wozniacki celebrates after winning against Britain's Laura Robson during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / PATRICK KOVARIK (Photo credit should read PATRICK KOVARIK/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Spain's Rafael Nadal serves to Germany's Daniel Brands during their French Tennis Open first round match at the Roland Garros stadium in Paris, on May 27, 2013. AFP PHOTO / MIGUEL MEDINA (Photo credit should read MIGUEL MEDINA/AFP/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Caroline Wozniacki of Denmark looks on in her Women's Singles match against Laura Robson of Great Britain during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Julian Finney/Getty Images)

  • 2013 French Open - Day Two

    PARIS, FRANCE - MAY 27: Daniel Brands of Germany plays a backhand in his Men's Singles match against Rafael Nadal of Spain during day two of the French Open at Roland Garros on May 27, 2013 in Paris, France. (Photo by Matthew Stockman/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    France's Jo-Wilfried Tsonga celebrates after winning agaisnt Slovenia's Aljaz Bedene during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / PATRICK KOVARIK (Photo credit should read PATRICK KOVARIK/AFP/Getty Images)

  • TENNIS-FRA-OPEN-MEN

    Spain's Rafael Nadal reacts after a point against Germany's Daniel Brands during a French tennis Open first round match on May 27, 2013 at the Roland Garros stadium in Paris. AFP PHOTO / THOMAS COEX (Photo credit should read THOMAS COEX/AFP/Getty Images)

  • Source: http://www.huffingtonpost.com/2013/05/27/john-tomic-bernard-father-barred-french-open-access_n_3342637.html

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    Work From Home Internet Marketing Strategies by Arianne Young ...

    How to Make Money Online with Internet Affiliate Marketing

    by: Arianne Young


    For internet entrepreneurs, there are many interweb marketing strategies to increase dealings and maximize profits online. You will discover the best internet marketing strategies in the present article. With people strategies, you will skyrocket your profits and improve rapidly your house based internet marketing business.

    Tip #1: Research Everything You Need to Know Effectively.

    It is discernable that research hot niche keywords to attract additional traffic, maximize the benefit of your pay per click (or PPC) campaigns, and find new hot niche markets with above average requirement are required in this moment strategy. Of course, that is the first valuable strategies you must do for your own housing centered web marketing business. With folks well-researches, you will can identify everything you must know for your markets, so much needs and want in the market. There much equipment on the internet to permit you to learn hot niche markets and keywords. The highest recommendation for coming across individuals markets and keywords is to use both of Overture and WordTracker keyword search ideas to construct a massive listing of keywords. With the list, you can analyse and evaluate the market, competitors and keywords.

    The initial key success of house based internet business is to discover niche keywords provided low competitors. With those keywords, you can: (1) Set up your high quality content website providing high quality and tightly targeted traffic (2) Improve your ranking in search engine engines (3) Build your unique & high class content/articles with keyword-rich (4) Create your triumphant pay-per-click campaign and (5) Build up profitable successful blog online.

    Tip #2: Approach the Front-Back Sell through Great Sale Letter.

    Second of the perfect internet marketing strategies you must concern is to provide a great and easy to understand market letter on your website. This web marketing strategy is all right about furnishing a excellent market letter with high conversion rate and builds your online mailing lists. The market letter on your website is the first place for visitors to walk within your products, services, testimonial, benefits and your required action. You should economy all required information for how properties are looking. You should definite without a doubt what you want visitors to do in your website. For example, you are able to want them to form your products, you want them to subscribe your mailing lists or you want them to download your bonuses. The utmost recommendation in such a strategy is to focus on how to transmute people visitors to buyers within your own sales letter. You can not find any dollars if you can not translate people visitors into your buyers. Also, you are losing your time to drive income to your website if you can not translate into sales. Remember, the more conversion rate you have, the more sales you get!

    Apart from trying to sell your products through sales letter, it is discernable the current you is planning to capture visitors' information in form to sell your packages or other products to them after they leave. Without capturing the information, you are losing the choices to earn money in the future.

    The real keys to your success in right now strategy are: to embark on a powerful sells letter with astronomical conversion rate and market products in the future. With capturing the visitors' information, the choices to motivate money in the coming years are opened.

    Tip #3: Do Not Reinvent the Wheel.

    The core concept of this strategy is who you do not reinvent the wheel all the time. You must utilize the complete use of others' expertise to maximize the opportunities to make considerable money online out of home based internet marketing business. There are many websites, expertise and a larger amount of successful entrepreneurs on the internet. You can ask them to minimize your mistakes and grow your property based interweb marketing business. The highly recommendation is to join other membership ones and utilise the others' expertise as a great deal as possible. The more you learn, the more you know! With others' support, you might minimize your mistakes and can grow your business easier.

    The real keys to your exploit in now strategy are: (1) to research effectively based on information from others and (2) utilise individuals others' expertise to minimize your mistakes and maximize your profits. Many studies reveal too those very successful internet entrepreneurs are prepared to help buyers who are serious and passionate in the internet re&wshyp;selling and success.

    Tip #4: Automate Your Home Based Internet Marketing Business.

    Without the automation web marketing strategy, not only you ought to get fewer sales, you only should not have more time to investigation innovations for new home founded interweb re&wshyp;selling businesses. By building house centered internet marketing sector which is totally automated. You can withdraw from your daily business as usual works and you will have more time to be on the look for more untapped niche markets and other opportunities. Many studies show who this strategy is the best of the highest quality web marketing strategies to develop your property based internet marketing business in the long term. The procedures of thumb, 80/20 rule, for your business are: (1) put 80 for growing your business.

    The real keys to your success in this strategy are: to find automated weapons to benefit you and automate your online business. With those tools, you am able to have more era to think and gain your business. Otherwise, you will dwell in the daily business as usual works.

    Tip #5: Improve Yourself Consistency.

    The last top internet marketing strategies for your home based internet marketing strategy is you. You are the most significant and valuable asset in your business. You have to improve yourself all the time. Learning anything and everything you seek to know for your business is a must. Also, you when not give up too quickly if you can not take in big traffic in the short term. Truly entrepreneurs are always appearing forward to the for a while go success. The online internet selling economy is a real business. With such a sense, you undergo to treat it as real business.

    The real keys to your success are to develop yourself, the best valuable asset in your business, and to build consistency your online internet marketing business always.

    Final thoughts, the best internet marketing strategies for your highly successful in housing based internet marketing business are: perfectly effective researches, front-back sell, smart utilization, automate effectively, and self-improvement consistency. With these things, there is no hesitation that you reach your goals. Be sure to be consistant and patient.

    Arianne Young is a creative income mentor who helps individuals all around the world!

    Did`nt Find What You Was Looking For Search Our Site Now!

    To Find out more about producing Money Online with Affiliate marketing online Visit Super Affiliate Marketing on the Internet

    Source: http://maw-new-super-affiliate-blog.com/work-from-home-internet-marketing-strategies-by-arianne-young

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    Valeant to buy Bausch + Lomb for $8.7B

    Canadian drugmaker Valeant Pharmaceuticals said Monday that it will pay $8.7 billion to buy Bausch + Lomb, one of the world's best-known makers of contact lenses, in a massive expansion of Valeant's smaller ophthalmology business.

    Valeant said the cash deal will help it capitalize on increasing demand for contact lenses and other products because of aging populations, growing demand in emerging markets and increasing rates of diabetes. Complications of the complex blood sugar disorder can damage the eyes over time.

    Investment firm Warburg Pincus, which leads an investment group that owns Bausch + Lomb, will receive $4.5 billion in cash. The remaining $4.2 billion will be used to repay Bausch + Lomb's debt.

    Reports that the purchase was in the works surfaced late last week, driving up shares of Valeant on Friday by 13.1 percent, to $84.47.

    The deal, which requires approval from regulators and other standard closing conditions, is expected to be completed in the third quarter. It will be financed with debt and about $1.5 billion to $2 billion in new stock.

    Valeant expects to achieve at least $800 million in annual cost savings by the end of next year, and said the acquisition will add to its profits immediately.

    Rochester, N.Y.-based Bausch + Lomb Holdings Inc. makes contact lenses, eye drugs and ophthalmic surgical devices. It will keep its name and become a division of Valeant Pharmaceuticals International Inc., which is based in Laval, Quebec.

    "I am confident that under their stewardship, the Bausch + Lomb brand will continue to stand for excellence and innovation in eye health," Brent Saunders, CEO of Bausch + Lomb, said in a statement.

    "Bausch + Lomb has undergone a profound transformation over the last few years," Saunders said. "We introduced innovative new products for patients, built a robust pipeline, expanded into new markets and strengthened our relationships with eye care professionals around the world."

    Valeant's ophthalmology business will be folded into the new Bausch + Lomb division. The combined global business would have 2013 revenue topping $3.5 billion on a pro forma basis, meaning the total of sales from both companies' eye care businesses for the full year.

    Much of that will come from Bausch + Lomb, which anticipates it will have revenue of about $3.3 billion this year. Bausch + Lomb expects adjusted earnings before interest, taxes, depreciation and amortization of about $720 million.

    The deal cements the combined business as one of the global leaders in eye care.

    Switzerland's Novartis AG had about $5 billion in combined 2012 revenue from its sales of Lucentis, a pricey biologic drug for treating the eye condition macular degeneration, and from its Alcon division. Alcon sells contact lenses and solutions, lenses implanted in the eye to treat near-sightedness and cataracts, ophthalmology drugs and surgical equipment.

    New Brunswick, N.J.-based Johnson & Johnson's Vistakon eye care division had 2012 revenue of about $3 billion. It sells Acuvue contact lenses, which the company claims are the world's most widely used brand.

    Allergan, based in Irvine, Calif., had about $2.7 billion in revenue last year, from its Refresh artificial tears and prescription drugs including Restasis for dry eyes and two medicines for treating glaucoma and excessive fluid pressure within the eye.

    After the deal closes, Saunders will become an adviser to Valeant to help with integrating Bausch + Lomb. Other senior Bausch + Lomb executives will join Valeant as well.

    The $8.7 billion purchase price is about 2 1/2 times the 2012 revenue of $3.55 billion reported by Valeant, which specializes in dermatology medicines. It also sells a range of brand-name and generic drugs, as well as nonprescription medicines.

    Valeant's CEO, J. Michael Pearson, said in a statement that the deal will make his company a world leader in both eye health and dermatology.

    "Bausch + Lomb's world-renowned brand, comprehensive portfolio of leading eye care products and promising late-stage pipeline are an ideal strategic fit for our current ophthalmology business," Pearson said.

    Bausch + Lomb had been taken private in 2007, when New York-based Warburg Pincus bought the struggling company for $3.67 billion.

    That happened after Bausch + Lomb had to recall its ReNu with MoistureLoc contact lens solution because it had been linked to dangerous fungal infections. Bausch + Lomb then paid out about $250 million to settle more than 600 lawsuits blaming the MoistureLoc solution for a potentially blinding infection of the cornea, the clear membrane over the pupil and the colored part of the eye.

    Bausch + Lomb has since worked to rebuild, most recently with a series of acquisitions.

    Last year, it narrowed its net loss to $68.3 million from $123.9 million in 2011. Revenue rose to $3.04 billion in 2012 from $2.85 billion.

    Two months ago, the company said it expected to go public again.

    Valeant has about 7,500 employees worldwide, while Bausch + Lomb has more than 11,000. The companies did not indicate whether the combination will result in job cuts.

    ___

    Follow Linda A. Johnson at http://twitter.comLindaJ_onPharma

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-05-27-Bausch%20and%20Lomb-Valeant/id-ff4a68f45e674846937dd26c140fb1d1

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    Work From Home Internet Marketing Strategies by Arianne Young ...

    How to Make Money Online with Internet Affiliate Marketing

    by: Arianne Young


    For internet entrepreneurs, there are many interweb marketing strategies to increase dealings and maximize profits online. You will discover the best internet marketing strategies in the present article. With people strategies, you will skyrocket your profits and improve rapidly your house based internet marketing business.

    Tip #1: Research Everything You Need to Know Effectively.

    It is discernable that research hot niche keywords to attract additional traffic, maximize the benefit of your pay per click (or PPC) campaigns, and find new hot niche markets with above average requirement are required in this moment strategy. Of course, that is the first valuable strategies you must do for your own housing centered web marketing business. With folks well-researches, you will can identify everything you must know for your markets, so much needs and want in the market. There much equipment on the internet to permit you to learn hot niche markets and keywords. The highest recommendation for coming across individuals markets and keywords is to use both of Overture and WordTracker keyword search ideas to construct a massive listing of keywords. With the list, you can analyse and evaluate the market, competitors and keywords.

    The initial key success of house based internet business is to discover niche keywords provided low competitors. With those keywords, you can: (1) Set up your high quality content website providing high quality and tightly targeted traffic (2) Improve your ranking in search engine engines (3) Build your unique & high class content/articles with keyword-rich (4) Create your triumphant pay-per-click campaign and (5) Build up profitable successful blog online.

    Tip #2: Approach the Front-Back Sell through Great Sale Letter.

    Second of the perfect internet marketing strategies you must concern is to provide a great and easy to understand market letter on your website. This web marketing strategy is all right about furnishing a excellent market letter with high conversion rate and builds your online mailing lists. The market letter on your website is the first place for visitors to walk within your products, services, testimonial, benefits and your required action. You should economy all required information for how properties are looking. You should definite without a doubt what you want visitors to do in your website. For example, you are able to want them to form your products, you want them to subscribe your mailing lists or you want them to download your bonuses. The utmost recommendation in such a strategy is to focus on how to transmute people visitors to buyers within your own sales letter. You can not find any dollars if you can not translate people visitors into your buyers. Also, you are losing your time to drive income to your website if you can not translate into sales. Remember, the more conversion rate you have, the more sales you get!

    Apart from trying to sell your products through sales letter, it is discernable the current you is planning to capture visitors' information in form to sell your packages or other products to them after they leave. Without capturing the information, you are losing the choices to earn money in the future.

    The real keys to your success in right now strategy are: to embark on a powerful sells letter with astronomical conversion rate and market products in the future. With capturing the visitors' information, the choices to motivate money in the coming years are opened.

    Tip #3: Do Not Reinvent the Wheel.

    The core concept of this strategy is who you do not reinvent the wheel all the time. You must utilize the complete use of others' expertise to maximize the opportunities to make considerable money online out of home based internet marketing business. There are many websites, expertise and a larger amount of successful entrepreneurs on the internet. You can ask them to minimize your mistakes and grow your property based interweb marketing business. The highly recommendation is to join other membership ones and utilise the others' expertise as a great deal as possible. The more you learn, the more you know! With others' support, you might minimize your mistakes and can grow your business easier.

    The real keys to your exploit in now strategy are: (1) to research effectively based on information from others and (2) utilise individuals others' expertise to minimize your mistakes and maximize your profits. Many studies reveal too those very successful internet entrepreneurs are prepared to help buyers who are serious and passionate in the internet re&wshyp;selling and success.

    Tip #4: Automate Your Home Based Internet Marketing Business.

    Without the automation web marketing strategy, not only you ought to get fewer sales, you only should not have more time to investigation innovations for new home founded interweb re&wshyp;selling businesses. By building house centered internet marketing sector which is totally automated. You can withdraw from your daily business as usual works and you will have more time to be on the look for more untapped niche markets and other opportunities. Many studies show who this strategy is the best of the highest quality web marketing strategies to develop your property based internet marketing business in the long term. The procedures of thumb, 80/20 rule, for your business are: (1) put 80 for growing your business.

    The real keys to your success in this strategy are: to find automated weapons to benefit you and automate your online business. With those tools, you am able to have more era to think and gain your business. Otherwise, you will dwell in the daily business as usual works.

    Tip #5: Improve Yourself Consistency.

    The last top internet marketing strategies for your home based internet marketing strategy is you. You are the most significant and valuable asset in your business. You have to improve yourself all the time. Learning anything and everything you seek to know for your business is a must. Also, you when not give up too quickly if you can not take in big traffic in the short term. Truly entrepreneurs are always appearing forward to the for a while go success. The online internet selling economy is a real business. With such a sense, you undergo to treat it as real business.

    The real keys to your success are to develop yourself, the best valuable asset in your business, and to build consistency your online internet marketing business always.

    Final thoughts, the best internet marketing strategies for your highly successful in housing based internet marketing business are: perfectly effective researches, front-back sell, smart utilization, automate effectively, and self-improvement consistency. With these things, there is no hesitation that you reach your goals. Be sure to be consistant and patient.

    Arianne Young is a creative income mentor who helps individuals all around the world!

    Did`nt Find What You Was Looking For Search Our Site Now!

    To Find out more about producing Money Online with Affiliate marketing online Visit Super Affiliate Marketing on the Internet

    Source: http://maw-new-super-affiliate-blog.com/work-from-home-internet-marketing-strategies-by-arianne-young

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    Wednesday, May 22, 2013

    Barbie Wedding Room

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    Source: http://www.hotgamesforgirls.com/play-barbie-wedding-room.html

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    Common food supplement fights degenerative brain disorders, study suggests

    May 21, 2013 ? Widely available in pharmacies and health stores, phosphatidylserine is a natural food supplement produced from beef, oysters, and soy. Proven to improve cognition and slow memory loss, it's a popular treatment for older people experiencing memory impairment. Now a team headed by Prof. Gil Ast and Dr. Ron Bochner of Tel Aviv University's Department of Human Molecular Genetics has discovered that the same supplement improves the functioning of genes involved in degenerative brain disorders, including Parkinson's disease and Familial Dysautonomia (FD).

    In FD, a rare genetic disorder that impacts the nervous system and appears almost exclusively in the Ashkenazi Jewish population, a genetic mutation prevents the brain from manufacturing healthy IKAP proteins -- which likely have a hand in cell migration and aiding connections between nerves -- leading to the early degeneration of neurons. When the supplement was applied to cells taken from FD patients, the gene function improved and an elevation in the level of IKAP protein was observed, reports Prof. Ast. These results were replicated in a second experiment which involved administering the supplement orally to mouse populations with FD.

    The findings, which have been published in the journal Human Molecular Genetics, are very encouraging, says Prof. Ast. "That we see such an effect on the brain -- the most important organ in relation to this disease -- shows that the supplement can pass through the blood-brain barrier even when administered orally, and accumulate in sufficient amounts in the brain."

    Slowing the death of nerve cells

    Already approved for use as a supplement by the FDA, phosphatidylserine contains a molecule essential for transmitting signals between nerve cells in the brain. Prof. Ast and his fellow researchers decided to test whether the same chemical, which is naturally synthesized in the body and known to boost memory capability, could impact the genetic mutation which leads to FD.

    Researchers applied a supplement derived from oysters, provided by the Israeli company Enzymotec, to cells collected from FD patients. Noticing a robust effect on the gene, including a jump in the production of healthy IKAP proteins, they then tested the same supplement on mouse models of FD, engineered with the same genetic mutation that causes the disease in humans.

    The mice received the supplement orally, every two days for a period of three months. Researchers then conducted extensive genetic testing to assess the results of the treatment. "We found a significant increase of the protein in all the tissues of the body," reports Prof. Ast, including an eight-fold increase in the liver and 1.5-fold increase in the brain. "While the food supplement does not manufacture new nerve cells, it probably delays the death of existing ones," he adds.

    Therapeutic potential for Parkinson's

    That the supplement is able to improve conditions in the brain, even when given orally, is a significant finding, notes Prof. Ast. Most medications enter the body through the blood stream, but are incapable of breaking through the barrier between the blood and the brain.

    In addition, the researchers say the supplement's positive effects extend beyond the production of IKAP. Not only did phosphatidylserine impact the gene associated with FD, but it also altered the level of a total of 2400 other genes -- hundreds of which have been connected to Parkinson's disease in previous studies.

    The researchers believe that the supplement may have a beneficial impact on a number of degenerative diseases of the brain, concludes Prof. Ast, including a major potential for the development of new medications which would help tens of millions of people worldwide suffering from these devastating diseases.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/q1h7TAfYouo/130521121511.htm

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    Search for Okla. tornado survivors nearly complete

    MOORE, Okla. (AP) ? Helmeted rescue workers raced Tuesday to complete the search for survivors and the dead in the Oklahoma City suburb where a mammoth tornado destroyed countless homes, cleared lots down to bare red earth and claimed 24 lives, including those of nine children.

    Scientists concluded the storm was a rare and extraordinarily powerful type of twister known as an EF5, ranking it at the top of the scale used to measure tornado strength. Those twisters are capable of lifting reinforced buildings off the ground, hurling cars like missiles and stripping trees completely free of bark.

    Residents of Moore began returning to their homes a day after the tornado smashed some neighborhoods into jagged wood scraps and gnarled pieces of metal. In place of their houses, many families found only empty lots.

    After nearly 24 hours of searching, the fire chief said he was confident there were no more bodies or survivors in the rubble.

    "I'm 98 percent sure we're good," Gary Bird said at a news conference with the governor, who had just completed an aerial tour of the disaster zone.

    Authorities were so focused on the search effort that they had yet to establish the full scope of damage along the storm's long, ruinous path.

    They did not know how many homes were gone or how many families had been displaced. Emergency crews had trouble navigating devastated neighborhoods because there were no street signs left. Some rescuers used smartphones or GPS devices to guide them through areas with no recognizable landmarks.

    The death toll was revised downward from 51 after the state medical examiner said some victims may have been counted twice in the confusion. More than 200 people were treated at area hospitals.

    By Tuesday afternoon, every damaged home had been searched at least once, Bird said. His goal was to conduct three searches of each building just to be certain there were no more bodies or survivors.

    The fire chief was hopeful that could be completed before nightfall, but the work was being hampered by heavy rain. Crews also continued a brick-by-brick search of the rubble of a school that was blown apart with many children inside.

    No additional survivors or bodies have been found since Monday night, Bird said.

    Survivors emerged with harrowing accounts of the storm's wrath, which many endured as they shielded loved ones.

    Chelsie McCumber grabbed her 2-year-old son, Ethan, wrapped him in jackets and covered him with a mattress before they squeezed into a coat closet of their house. McCumber sang to her child when he complained it was getting hot inside the small space.

    "I told him we're going to play tent in the closet," she said, beginning to cry.

    "I just felt air so I knew the roof was gone," she said Tuesday, standing under the sky where her roof should have been. The home was littered with wet gray insulation and all of their belongings.

    "Time just kind of stood still" in the closet, she recalled. "I was kind of holding my breath thinking this isn't the worst of it. I didn't think that was it. I kept waiting for it to get worse."

    "When I got out, it was worse than I thought," she said.

    Gov. Mary Fallin lamented the loss of life, especially the children who were killed, but she celebrated the town's resilience.

    "We will rebuild, and we will regain our strength," Fallin said.

    In describing the bird's-eye view of the damage, the governor said many houses were "taken away," leaving "just sticks and bricks, basically. It's hard to tell if there was a structure there or not."

    From the air, large stretches of town could be seen where every home had been cut to pieces. Some homes were sucked off their concrete slabs. A pond was filled with piles of wood and an overturned trailer.

    Also visible were large patches of red earth where the tornado scoured the land down to the soil. Some tree trunks were still standing, but the winds ripped away their leaves, limbs and bark.

    In revising its estimate of the storm's power, the National Weather Service said the tornado had winds of at least 200 mph and was on the ground for 40 minutes.

    The agency upgraded the tornado from an EF4 on the enhanced Fujita scale based on reports from a damage-assessment team, said spokeswoman Keli Pirtle. Monday's twister was at least a half-mile wide. It was the nation's first EF5 tornado of 2013.

    Other search-and-rescue teams concentrated on Plaza Towers Elementary, where the storm ripped off the roof, knocked down walls and destroyed the playground as students and teachers huddled in hallways and bathrooms.

    Seven of the nine dead children were killed at the school, but several students were pulled alive from under a collapsed wall and other heaps of mangled debris. Rescue workers passed the survivors down a human chain of parents and neighborhood volunteers. Parents carried children in their arms to a triage center in the parking lot. Some students looked dazed, others terrified.

    Neither Plaza Towers nor another school in Oklahoma City that was not as severely damaged had reinforced storm shelters, or safe rooms, said Albert Ashwood is director of the Oklahoma Department of Emergency Management.

    More than 100 schools across the state do have safe rooms, he said, explaining that it's up to each jurisdiction to set spending priorities.

    Ashwood said a shelter would not necessarily have saved more lives at Plaza Towers.

    "When you talk about any kind of safety measures ... it's a mitigating measure, it's not an absolute," he told reporters. "There's not a guarantee that everyone will be totally safe."

    Officials were still trying to account for a handful of children not found at the school who may have gone home early with their parents, Bird said.

    On the streets of Moore, evidence of the storm's fury stretched in every direction: Roofs were torn off houses, exposing metal rods left twisted like pretzels. Cars sat in heaps, crumpled and sprayed with caked-on mud. Insulation and siding was piled up against any walls still standing. Yards were littered with pieces of wood, nails and pieces of electric poles.

    President Barack Obama pledged to provide federal help and mourned the death of young children who were killed while "trying to take shelter in the safest place they knew ? their school."

    The town of Moore "needs to get everything it needs right away," he said Tuesday.

    Moore has been one of the fastest-growing suburbs of Oklahoma City, attracting middle-income families and young couples looking for stable schools and affordable housing. The town's population has grown over the last decade as developers built subdivisions for people who wanted to avoid the urban problems and schools of Oklahoma City but couldn't afford pricier Norman, the college town next door.

    Many residents commute to jobs in Oklahoma City or to Tinker Air Force Base, about 20 minutes away.

    ___

    Associated Press writers Tim Talley, Ramit Plushnick-Masti and Nomaan Merchant, and Associated Press photographer Sue Ogrocki contributed to this report.

    Source: http://news.yahoo.com/search-okla-tornado-survivors-nearly-complete-005223327.html

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    BenQ MX518


    As the middle-resolution model of three recently released budget BenQ DLP data projectors, the BenQ MX518 has much in common with the BenQ MS517 and BenQ MW519: respectable brightness; a good price for the resolution; data image quality suitable for typical classroom presentations and video suitable for shorter clips; feeble audio; a good assortment of ports, 3D compatibility (you supply the glasses), and a variety of eco-friendly features. Like its siblings, it's a solid choice as a low-priced educational (or business) projector.

    The MX518 provides XGA (1,024 by 768 pixel) resolution, between the MS-517's SVGA (800 by 600) and the MW519's WXGA (1,280 by 800) resolution. Like the other two models, it's rated at 2,800 lumens of brightness.

    The MX518 is all black, with rounded corners and a slightly bowed top. It has a very modest manual zoom (1.1:1), and the focus was fairly responsive. At 8.7 by 11.9 by 4.4 inches (HWD) and 5.1 pounds, the MX518 is quite portable, though it lacks a soft carrying case. It should be easy enough to tote within a school or on trips.

    The MX518 has a good selection of ports for a low-priced projector, including HDMI; composite video/audio; S-video; two VGA inputs to connect with computers and one to connect with a monitor; an audio-out jack, an RS232 jack, and a USB type B connector for connecting with a computer.

    Testing
    The image filled our test screen (about 60 inches on a diagonal) with the projector about seven feet away from the screen. As befitting its 2,800-lumen rated brightness, it was able to stand up to considerable ambient light without it looking degraded.

    In data testing, I ran our standard suite of DisplayMate tests over a VGA connection, and then over an HDMI connection. With VGA, when I first loaded the tests using default settings, I saw extensive pixel jitter?moving, thin dark lines appearing to flicker across the screen. I went into the menu and adjusted the Phase setting, and only a trace of the jitter remained. When I switched to HDMI, the jitter completely disappeared.

    In our type test, text was slightly blurred at the second smallest white-on-black size, and barely readable at the smallest. As for color, there was some mild green tinting to gray images in both VGA and (to a lesser extent) HMDI. Colors, most notably reds and yellows, generally looked somewhat dull, regardless of the projector's mode or connection type.

    One issue that I noted, which is often an issue in DLP projectors, is the rainbow effect, in which bright areas seen against dark backgrounds seem to break up into little red-green-blue rainbows. As is typical, in data images it wasn't severe enough to be problematic, even to people who are sensitive to it.

    Video
    The rainbow effect was also visible in video images. Rainbow artifacts were apparent enough in some scenes that people who are sensitive to the effect are likely to be distracted by it, making this projector best for relatively short clips as part of a presentation or lecture. Another issue I encountered was posterization, rapid changes in color from one part of an image to another where they should be gradual.

    Another impediment to video is this projector's feeble 2-watt audio system. It makes the MX518 best for a small room or if you're sitting quite close to the projector. It does have an audio-out port, so you could always hook it to powered external speakers if need be.

    The MX518 has several eco-friendly features that can conserve power and help extent lamp life, up to a claimed maximum of 6,500 hours. EcoBlank mode lets teachers easily take a break from a presentation, blanking the screen out and lowering energy consumption up to 70% while paused. The projector will also automatically enter EcoBlank mode after 3 minutes without a signal. SmartEco mode automatically adjusts lamp brightness depending on lighting conditions.

    The MX518 is 3D-capable, with support for 3D Blu-Ray via HDMI as well as NVIDIA 3DTV Play, enabling it to display 3D content from NVIDIA 3D Vision. The active shutter 3D glasses are not included, and can cost up to $70 per pair, so equipping a class with them could prove a pricey proposition.

    The Editors' Choice Epson PowerLite 93+ is not 3D capable, but being LCD based, it is immune from the rainbow effect. It provides superb audio and video quality, and loud audio, too. Another XGA projector, the ViewSonic PJD5234, is very similar to the MX518 in features and performance.

    All three of the new BenQ budget data projectors are capable of handling the demands of a classroom, providing multiple connection choices, solid data image quality, and good enough video for typical school use. They're 3D capable, with eco-friendly features that should prolong lamp life. On the downside are very soft audio and the rainbow effect. Choosing between them mostly depends on the level of detail you need to display?for typical presentations, the BenQ MX518 should do fine?and how much you're willing to spend.

    The MX518 is 3D-capable, with support for 3D Blu-Ray via HDMI as well as NVIDIA 3DTV Play, enabling it to display 3D content from NVIDIA 3D Vision. The active shutter 3D glasses are not included, and can cost up to $70 per pair, so equipping a class with them could prove a pricey proposition.

    The Editors' Choice Epson PowerLite 93+ is not 3D capable, but being LCD based, it is immune from the rainbow effect. It provides superb audio and video quality, and loud audio, too. Another XGA projector, the ViewSonic PJD5234, is very similar to the MX518 in features and performance.

    All three of the new BenQ budget data projectors are capable of handling the demands of a classroom, providing multiple connection choices, solid data image quality, and good enough video for typical school use. They're 3D capable, with eco-friendly features that should prolong lamp life. On the downside are very soft audio and the rainbow effect. Choosing between them mostly depends on the level of detail you need to display?for typical presentations, the BenQ MX518 should do fine?and how much you're willing to spend.

    Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/AYIwZHKwypk/0,2817,2418318,00.asp

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